How To Find Gene Promoter

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GitHub - broadinstitute/ABC-Enhancer-Gene-Prediction: Cell ...

In the absence of expression data, DNase-seq and H3K27ac ChIP-seq at the gene promoter can be used as a proxy for expression. We suggest only considering enhancer-gene connections for genes with sufficiently active promoters (for instance in the top 60% of gene promoters in the cell type) Quantile Normalization

Related News

Mining the Selective Remodeling of DNA Methylation in Promoter Regions to Identify Robust Gene-Level Associations With Phenotype

1 month ago - A recent study found that the DNA methylation difference of the gene body and promoter region has a strong correlation with gene expression. In this study, we proposed a Statistical difference of DNA ......detail

Promoter extract

4 years ago - Note each gene may have different isoforms = different TSSs. The pipeline extracts the promoters for each isoform, and merges overlapping into a single promoter. *_not_found.txt file has gene names ......detail

Genes can identify coded information

14 days ago - the researchers found that genes were also able to filter out some signals. The mechanics of this are both straightforward and mysterious.The researchers could tell that when a second protein was ......detail

Muscle-Specific Promoters for Gene Therapy

1 year ago - This review focuses on the development and improvement of muscle-specific promoters based on skeletal muscle α-actin, muscle creatine kinase, and desmin genes, as well as other genes expressed in ......detail

Findings Show Gene Behavior Depends on Coded Info in Signals and Could be Harnessed to Fine-Tune Biotech

Findings Show Gene Behavior Depends on Coded Info in Signals and Could be Harnessed to Fine-Tune Biotech18 days ago - Study results showed how different light patterns can produce very different outcomes in terms of gene activity....detail

Genes can respond to coded information in signals – or filter them out entirely

19 days ago - Researchers have demonstrated that genes are capable of identifying and responding to coded information in light signals, as well as filtering out some signals entirely. The study shows how a single ......detail

Phenotype of mutations in the promoter region of the β-globin gene

4 years ago - Aims In this report we describe the mutations found in the promoter region of the β-globin gene in a single hospital in Madrid. Methods Between 1998 and 2015, more than 9000 blood samples were ......detail

Comparative Analysis of Insulin Gene Promoters: Implications for Diabetes Research

23 days ago - The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ......detail

Genes can respond to coded information in signals

17 days ago - the researchers found that genes were also able to filter out some signals. The mechanics of this are both straightforward and mysterious. The researchers could tell that when a second protein was ......detail

CRISPR/Cas9 and mRNA-Based Technology Allows for Gene Editing and Expression in CLL Cells

18 hours ago - CRISPR/Cas9 and mRNA-based gene editing and expression was found to be feasible in evaluating primary chronic lymphocytic leukemia cells....detail

Genes can respond to coded information in signals—or filter them out entirely

19 days ago - The researchers could tell that when a second protein attached to the promoter region of the gene, some frequencies of light pulses did not trigger the production of fluorescent proteins....detail

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